Choice of Insulin Coformulations: Biphasic Insulin Versus Insulin-GlP1RA

Authors

  • Sanjay Kalra Department of Endocrinology, Bharti Hospital, Karnal, India; University Centre for Research & Development, Chandigarh University, Mohali, India;
  • Sambit Das Department of Endocrinology, Kalinga Institute of Medical Sciences, Bhubaneshwar, India;
  • Saptarshi Bhattacharya Department of Endocrinology, Apollo Indraprastha Hospitals, New Delhi, India;
  • Nitin Kapoor Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India; Non-communicable disease unit, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.

DOI:

https://doi.org/10.47391/JPMA.25-36

Abstract

This communication presents a pragmatic approachto describe the phenotypes which match with preferential usage of dual phase insulin or basal insulin+ glucagon-like peptide 1 receptor agonist (GLP1RA)coformulations. A comprehensive evaluation,including severity and style of glycaemia, clinical presentation, comorbidities, complications, and culinary preference, allows efficient choice of insulin formulation. This framework helps in initiation,intensification and interchange of injectable therapy,in an apt, and ept, manner.

Keywords: BIAsp, GLP1RA, glargine, insulin, Biphasic insulin, IGlarLixi, lixisenatide, IDegAsp, LisproMix,IDegLira, person centred care, premixed insulin.

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Published

2025-04-27

How to Cite

Sanjay Kalra, Sambit Das, Saptarshi Bhattacharya, & Nitin Kapoor. (2025). Choice of Insulin Coformulations: Biphasic Insulin Versus Insulin-GlP1RA. Journal of the Pakistan Medical Association, 75(05), 827–828. https://doi.org/10.47391/JPMA.25-36

Issue

Vol. 75 No. 05 (2025): MAY

Section

PRIMARY CARE DIABETES

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Copyright (c) 2025 Journal of the Pakistan Medical Association

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This work is licensed under a Creative Commons Attribution 4.0 International License.