Vacuum-assisted closure: a weapon in the arsenal of orthopaedic surgeons in the treatment of Gustilo-Anderson III-B fractures Authors Muhammad Mannan Ali Khan Department of Orthopaedics, Dow University of Health Sciences, Karachi, Pakistan Badaruddin Sahito Department of Orthopaedics, Dow University of Health Sciences, Karachi, Pakistan Tariq ali Bhatti Department of Orthopaedics, Dow University of Health Sciences, Karachi, Pakistan Husnain Ali Department of Orthopaedics, Dow University of Health Sciences, Karachi, Pakistan Waqar Ali Department of Orthopaedics, Dow University of Health Sciences, Karachi, Pakistan Syed Mohammad Mohtashim Ali Department of Orthopaedics, Dow University of Health Sciences, Karachi, Pakistan DOI: https://doi.org/10.47391/JPMA.22419 Keywords: Gustilo Anderson III-B, Vacuum Assisted Closure (VAC), Open fracture, Coverage Abstract The study aimed to assess the benefit of negative pressure dressing in the management of Gustilo Anderson type III-B open fractures. This prospective case series was conducted between March 2023 and March 2024 in the Department of Orthopaedics, Dr Ruth K M Pfau Civil Hospital, Karachi, in which records of 32 patients with open fractures treated with vacuum-assisted closure (VAC) dressing, who were admitted to the orthopaedic department, were analysed. The study showed that VAC dressing plays a beneficial role in the treatment of open fractures and reduces the need for large grafts and flaps for coverage by decreasing the size of the wound through contraction and covering the exposed bone with granulation tissue, which can then be covered by a split skin graft. VAC has provided an alternative for the lack of expertise and time-consuming procedures required for the coverage of open fractures. Keywords: Gustilo Anderson III-B, Vacuum Assisted Closure (VAC), Open fracture, Coverage. Downloads Full Text Article Published 2026-07-12 How to Cite Ali Khan, M. M., Sahito, B., Bhatti, T. ali, Ali, H., Ali, W., & Ali, S. M. M. (2026). Vacuum-assisted closure: a weapon in the arsenal of orthopaedic surgeons in the treatment of Gustilo-Anderson III-B fractures. Journal of the Pakistan Medical Association, 76(8), 1365–1368. https://doi.org/10.47391/JPMA.22419 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 76 No. 8 (2026): AUGUST Section CASE SERIES License Copyright (c) 2026 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.