Ovarian leiomyoma- An uncommon tumour Authors Mehreen Yousaf Rana Department of Obstetrics and Gynaecology, Ziauddin University Hospital, Karachi, Pakistan Saima Hanan Department of Obstetrics and Gynaecology, Ziauddin University Hospital, Karachi, Pakistan DOI: https://doi.org/10.47391/JPMA.21245 Keywords: Ovary, Leiomyoma, Pathological examination Abstract Primary ovarian leiomyoma is a rare benign tumour of the ovary seen in women between 20 and 65 years of age. We report a case of an ovarian leiomyoma in a 30 years old woman who presented with lower abdominal pain. Ultrasound scan revealed a heterogenous adnexal mass of 12x10cm, raising the possibility of dermoid cyst/teratoma. CA-125 level was 20.81 IU/ml. Laparoscopic removal of an irregular, white, stony hard ovarian mass was performed and histopathological examination confirmed the diagnosis of primary ovarian leiomyoma. Less than 100 cases have been reported in literature so far, including one from Pakistan. The tumour is usually asymptomatic and often misdiagnosed prior to surgical resection, therefore, the diagnosis is frequently made incidentally on histopathology. This rare tumour of the ovary should be considered in the differential diagnoses of solid ovarian masses and surgical intervention with ovary preserving technique is important in young patients. Keywords: Ovary, Leiomyoma, Pathological examination. Author Biography Mehreen Yousaf Rana, Department of Obstetrics and Gynaecology, Ziauddin University Hospital, Karachi, Pakistan Downloads Full Text Article Published 2026-03-26 How to Cite Mehreen Yousaf Rana, & Hanan, S. (2026). Ovarian leiomyoma- An uncommon tumour. Journal of the Pakistan Medical Association, 76(04), 592–594. https://doi.org/10.47391/JPMA.21245 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 76 No. 04 (2026): APRIL Section CASE REPORT License Copyright (c) 2026 Journal of the Pakistan Medical Association This work is licensed under a Creative Commons Attribution 4.0 International License.