Gorham-Stout disease: a textbook presentation of a rare disease in Pakistan

Authors

  • Muhammad Ibrahim Department of Orthopaedic and Trauma, Rehman Medical Institute, Peshawar, Pakistan
  • Muhammad Usman Department of Orthopaedic and Trauma, Rehman Medical Institute, Peshawar, Pakistan
  • Hawwa Khan Department of Orthopaedic and Trauma, Rehman Medical Institute, Peshawar, Pakistan
  • Faryal Javaid Department of Pathology, Rehman Medical Institute, Peshawar, Pakistan
  • Maria Tasneem Department of Pathology, Rehman Medical Institute, Peshawar, Pakistan
  • Zeeshan Khan Department of Orthopaedic and Trauma, Rehman Medical Institute, Peshawar, Pakistan

DOI:

https://doi.org/10.47391/JPMA.20212

Keywords:

Gorham Stout Syndrome, Massive osteolysis, Rare disease

Abstract

Gorham-Stout disease is an exceptionally rare disease which is characterised by massive osteolysis of the bone, oedema, and in severe cases pleural effusion and chylothorax. Its aetiopathology is unknown, and no specific treatment has been modulated thus far. We report the case of a 17-year-old male with osteolysis in the bones of his entire left arm and persistent chylothorax. Due to the late presentation and patient’s desire for a better quality of life, amputation was the only choice left for treatment. This case was evaluated and treated at the Orthopaedic Surgery and Trauma department of Rehman Medical Institute in Peshawar, Pakistan.

Key words: Gorham Stout Syndrome, Massive osteolysis, Rare disease.

Published

2025-01-26

How to Cite

Muhammad Ibrahim, Muhammad Usman, Hawwa Khan, Faryal Javaid, Maria Tasneem, & Zeeshan Khan. (2025). Gorham-Stout disease: a textbook presentation of a rare disease in Pakistan. Journal of the Pakistan Medical Association, 75(02), 307–310. https://doi.org/10.47391/JPMA.20212

Issue

Section

CASE REPORT