Accumulation of 131Iodine in the nasolacrimal sac/duct after radioiodine therapy for papillary thyroid cancer Authors Sharjeel Usmani Department of Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman. Anjali Jain Department of Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman Khulood Al Riyami Department of Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman Sofiullah Abubakar Department of Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman DOI: https://doi.org/10.47391/JPMA.23-22 Abstract SPECT/CT is a powerful tool for assessing unexpected concentrations of radioiodine resulting from benign uptake in organs with sodium-iodide symporter (NIS) expression. We report a case of accumulation of 131Iodine in the nasolacrimal sac/duct after radioiodine therapy for papillary thyroid cancer. A whole-body scan was taken 3 days after the administration of 5.5 GBq of 131Iodine. SPECT/CT images localized the focal tracer uptake in the nasolacrimal sac/duct likely due to nasolacrimal duct obstruction secondary to prior radioiodine or iodine therapies. Hybrid SPECT/CT allows precise anatomical localization and help differentiate benign mimics of disease, which can alter patient management. Keywords: 131Iodine SPECT-CT, thyroid cancer, papillary thyroid cancer, nasolacrimal duct obstruction Downloads Full Text Article Published 2023-02-15 How to Cite Usmani , S., Jain, A., Al Riyami, K., & Abubakar, S. (2023). Accumulation of 131Iodine in the nasolacrimal sac/duct after radioiodine therapy for papillary thyroid cancer. Journal of the Pakistan Medical Association, 73(3), 713–714. https://doi.org/10.47391/JPMA.23-22 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 73 No. 3 (2023): March Section IMAGING CORNER