Brain morphometric changes in patients with fibromyalgia Authors Kudret Cem Karayol Department of Physical Therapy and Rehabilitation, Harran University, Sanliurfa, Turkey Sunay Sibel Karayol Department of Radiology, Harran University, Sanliurfa, Turkey DOI: https://doi.org/10.47391/JPMA.273 Abstract The aim of this study was to determine whether there is a decrease or an increase in the volume of different regions of the brain by comparing brain morphometry ofpatients diagnosed with Fibromyalgia Syndrome and healthy control subjects. The study included 23 female patients who were diagnosed with fibromyalgia, and 18 females, age-matched healthy subjects. Structural Mitral Regurgitation data was processed using Surface-Based Morphometry (SBM) on the Freesurfer 6.0 programme (http://surfer.nmr.mgh.harvard.edu). As a result of the surface-based analyses, a statistically significant reduction was determined in the Fibromyalgia Syndrome patient group in some brain region. A statistically signficant increase was determined in the FMS patient group with respect to the left anterior occipital sulcus volume, left inferior temporal gyrus thickness and left anterior occipital sulcus area. The results of this study showed that FMS affected brain morphometry through the brain central pain mechanisms and the normal brain morphology was changed because of atrophy in some areas and hypertrophy in some areas. Keywords:Brain MRI, brain morphometry, fibromyalgia pain. Downloads Full Text Article Published 2022-09-15 How to Cite Kudret Cem Karayol, & Sunay Sibel Karayol. (2022). Brain morphometric changes in patients with fibromyalgia. Journal of the Pakistan Medical Association, 72(10), 2086–2089. https://doi.org/10.47391/JPMA.273 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Issue Vol. 72 No. 10 (2022): OCTOBER Section RESEARCH ARTICLE